For the first time in recent years, the game includes the addition of playable 125cc and 250cc support classes. MotoGP '07 for the PlayStation 2 had a reputation for emphasis on simulation in contrast to the MotoGP titles published by THQ, which have a reputation for arcade gameplay. MotoGP '08 is reported to balance these different styles and allow the player to configure an emphasis towards their desired gameplay.

For the first time in recent years, the game includes the addition of playable 125cc and 250cc support classes. MotoGP '07 for the PlayStation 2 had a reputation for emphasis on simulation in contrast to the MotoGP titles published by THQ, which have a reputation for arcade gameplay. MotoGP '08 is reported to balance these different styles and allow the player to configure an emphasis towards their desired gameplay.