The 4th entry in the RPG series, Mana Khemia is different from the previous Atelier Iris games. Mana Khemia is a campus sim style RPG, where you can interact with classmates and professors to complete academic quests. You play as Vayne Aurelius, a novice alchemist who was invited to attend Al - Revis Academy. At the academy, Vayne will meet human and not so human alchemists, and together you will solve the mysteries of alchemy.

The 4th entry in the RPG series, Mana Khemia is different from the previous Atelier Iris games. Mana Khemia is a campus sim style RPG, where you can interact with classmates and professors to complete academic quests. You play as Vayne Aurelius, a novice alchemist who was invited to attend Al - Revis Academy. At the academy, Vayne will meet human and not so human alchemists, and together you will solve the mysteries of alchemy.