Genius Yamada, the evil genius scientist who was supposed to have been repelled in the previous title, has once again raided the You&Me Kamiyoga game center and taken over the video game world. However, Yuki Ito, a clerk at the arcade, anticipates the situation and activates a program she has prepared to fight off Genius Yamada. JALECO's game characters gather again to retake the game world, but due to some mistake, Yuki Ito herself has also entered the game world.

Genius Yamada, the evil genius scientist who was supposed to have been repelled in the previous title, has once again raided the You&Me Kamiyoga game center and taken over the video game world. However, Yuki Ito, a clerk at the arcade, anticipates the situation and activates a program she has prepared to fight off Genius Yamada. JALECO's game characters gather again to retake the game world, but due to some mistake, Yuki Ito herself has also entered the game world.